Ingredent :- Drotaverine Hydrochloride
Used for :- DROTIN 40MG TABLET – Used to relieve spasms of smooth muscles in conditions like renal colic, biliary colic, and spasmodic dysmenorrhea.
Packing of 10 tablets strip
1. Indications
– Menstrual Pain (Dysmenorrhea): Provides relief from painful menstrual cramps by relaxing the uterine muscles.
– Abdominal Pain: Alleviates discomfort caused by smooth muscle spasms in the gastrointestinal tract.
– Renal Colic: Eases pain associated with kidney stones by relaxing the smooth muscles of the urinary tract.
– Biliary Colic: Relieves pain due to gallstones by relaxing the smooth muscles of the gallbladder and bile ducts.
– Gastrointestinal Colic: Reduces pain from spasms in the intestines, often associated with conditions like irritable bowel syndrome.
– Cervical Spasm During Labor: Used to manage cervical spasms during labor, aiding in smoother delivery.
2. Benefits
DROTIN 40MG TABLET offers several therapeutic benefits:
– Effective Pain Relief: Provides targeted relief from pain caused by smooth muscle spasms in various organs.
– Improved Mobility: Alleviates discomfort, enabling patients to engage in daily activities with reduced pain.
– Non-Sedative: Unlike some pain relievers, it does not cause drowsiness, allowing patients to remain alert.
– Minimal Side Effects: Generally well-tolerated with a low incidence of side effects when used as directed.
3. Dosage and Administration
The dosage of DROTIN 40MG TABLET should be determined by a healthcare professional based on the individual’s condition:
– Recommended Dosage: Typically, 1 to 2 tablets taken 2 to 3 times daily.
– Administration: Swallow the tablet whole with water. It can be taken with or without food.
– Missed Dose: If a dose is missed, take it as soon as remembered unless it’s almost time for the next dose. Do not double the dose to make up for a missed one.
4. Mechanism of Action
DROTIN 40MG TABLET contains drotaverine, a phosphodiesterase-4 (PDE4) inhibitor:
– Smooth Muscle Relaxation: Inhibits PDE4, leading to increased levels of cyclic adenosine monophosphate (cAMP), which relaxes smooth muscles.
– Pain Reduction: By relaxing the smooth muscles, it reduces the spasms and associated pain in various organs.
– Targeted Action: Acts specifically on smooth muscles without affecting skeletal muscles, minimizing side effects.
5. Side Effects
While DROTIN 40MG TABLET is generally well-tolerated, some individuals may experience side effects:
– Common Side Effects: Nausea, vomiting, dry mouth, dizziness, and constipation.
– Serious Side Effects: Allergic reactions such as rash, itching, swelling of the face, lips, tongue, or throat, which may cause difficulty in breathing.
– Cardiovascular Effects: Changes in pulse rate and a sudden drop in blood pressure.
– Neurological Effects: Headache and difficulty in breathing.
– Rare Effects: Anemia, decreased urine output, and gastroesophageal reflux disease (GERD).
6. Precautions
Before using DROTIN 40MG TABLET, consider the following precautions:
– Allergy: Do not use if allergic to drotaverine or any other component of the tablet.
– Heart Conditions: Use with caution in patients with heart failure or low cardiac output.
– Liver and Kidney Impairment: Exercise caution in patients with liver or kidney disease; dosage adjustments may be necessary.
– Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
– Drug Interactions: Inform the doctor about all other medications being taken, as drotaverine may interact with certain drugs.
7. Conclusion
In conclusion, DROTIN 40MG TABLET is an effective antispasmodic medication used to relieve pain and discomfort caused by smooth muscle spasms in various parts of the body. Its targeted action on smooth muscles provides relief from conditions such as menstrual cramps, abdominal pain, and renal colic. By following the prescribed dosage and considering the necessary precautions, patients can benefit from the therapeutic effects of DROTIN 40MG TABLET while minimizing potential risks. Always consult a healthcare professional before starting any new medication to ensure its suitability for your specific condition.









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