LAM PLUS H TABLET

Ingredent :- Losartan 50mg + Hydrochlorothiazide 12.5mg

Used for :-  LAM PLUS H TABLET – Used for the treatment of hypertension.

Packing of 10 tablets strip

1. Indications
   – Hypertension: Indicated for the treatment of essential hypertension, particularly in cases where monotherapy is insufficient.

   – Cardiovascular Risk Reduction: Helps in reducing the long-term risk of stroke and heart disease associated with elevated blood pressure.

   – Fluid Overload: Beneficial in managing mild fluid retention in hypertensive patients.

2. Benefits
The use of LAM PLUS H TABLET offers significant health advantages:

   – Enhanced Blood Pressure Control: Combines two mechanisms—vasodilation and diuresis—for more effective management of blood pressure.

   – Cardioprotective: Reduces stress on the heart and arteries, lowering the likelihood of cardiovascular complications.

   – Renoprotective: Slows the progression of kidney damage in hypertensive patients, especially those with comorbid diabetes.

   – Simplified Dosing: Offers the convenience of two antihypertensive actions in a single tablet, improving adherence.

3. Dosage and Administration
Proper administration is crucial for therapeutic success:

   – Recommended Dosage: Typically, one tablet once daily. Dosage may vary depending on the patient’s response and physician’s guidance.

   – Administration: Taken orally, preferably in the morning to avoid nocturnal urination caused by the diuretic component.

   – Missed Dose: If a dose is missed, take it as soon as remembered. If it’s near the next scheduled dose, skip the missed one—do not double up.

4. Mechanism of Action
LAM PLUS H TABLET exerts its antihypertensive effects via dual pathways:

   – ARB Component: Blocks the angiotensin II receptor, preventing vasoconstriction and thereby relaxing the blood vessels.

   – Diuretic Component: Promotes the excretion of sodium and water through the kidneys, reducing blood volume and pressure.

   – Synergistic Effect: The two components work together to enhance overall efficacy and blood pressure reduction.

5. Side Effects
While generally well-tolerated, some patients may experience side effects:

   – Electrolyte Imbalance: May cause low levels of potassium or sodium, requiring periodic monitoring.

   – Dizziness or Lightheadedness: Especially upon standing, due to blood pressure lowering effects.

   – Increased Urination: Common due to the diuretic effect, particularly during the first few days of therapy.

   – Fatigue or Weakness: Occasionally reported during treatment initiation.

   – Rare Reactions: Hypersensitivity, muscle cramps, or gout may occur in sensitive individuals.

6. Precautions
Before initiating LAM PLUS H TABLET, consider these safety precautions:

   – Kidney Function: Should be used with caution in patients with impaired kidney function; regular monitoring is advised.

   – Liver Disease: Dose adjustments may be needed in individuals with liver dysfunction.

   – Electrolyte Monitoring: Regular checks for potassium and sodium levels are recommended to prevent imbalances.

   – Pregnancy and Breastfeeding: Not recommended during pregnancy; consult a doctor if breastfeeding.

   – Drug Interactions: Caution with other antihypertensives, lithium, or NSAIDs which may alter drug effectiveness or increase toxicity risk.

7. Conclusion
In conclusion, LAM PLUS H TABLET is an effective dual-action antihypertensive medication that combines vasodilation and diuretic action to manage high blood pressure efficiently. Its benefits extend beyond simple blood pressure control by offering cardiovascular and renal protection. Regular monitoring and adherence to prescribed dosage enhance therapeutic outcomes while minimizing potential side effects.