CORALAN 5 TABLET

Ingredent :- Ivabradine

Use for :- CORALAN 5 TABLET – Used for the treatment of angina pectoris.

Units of :- Packing of 10 tablets strip

1. Indications
   – Chronic Stable Angina: Used to reduce the frequency of angina attacks by decreasing myocardial oxygen consumption.

   – Heart Failure: Prescribed for patients with chronic heart failure to improve symptoms and reduce hospitalization risk.

   – Elevated Heart Rate: Helps in lowering the resting heart rate in patients with cardiovascular disease when beta-blockers are contraindicated or insufficient.

  
2. Benefits
CORALAN 5 TABLET offers several benefits for patients with heart-related ailments:

   – Heart Rate Reduction: Specifically slows the heart rate without affecting blood pressure or myocardial contractility.

   – Improved Exercise Tolerance: Patients experience less chest pain and better physical activity capacity.

   – Symptom Relief: Reduces symptoms like palpitations, chest tightness, and fatigue related to heart conditions.

   – Safety Profile: Generally well-tolerated, with minimal effects on blood pressure, making it suitable for many cardiac patients.

  
3. Dosage and Administration
Proper administration is key for optimal therapeutic effect:

   – Recommended Dosage: Typically starts with 5 mg twice daily. The dose may be adjusted by the physician based on heart rate response and tolerance.

   – Administration: Should be taken orally with water, preferably at the same times each day.

   – Missed Dose: If a dose is missed, take it as soon as remembered unless it is near the time of the next dose. Do not double doses.

  
4. Mechanism of Action
CORALAN 5 TABLET works by selectively inhibiting the If current in sinoatrial node cells:

   – If Current Inhibition: Slows spontaneous pacemaker activity in the heart’s natural pacemaker, leading to reduced heart rate.

   – Selective Action: Does not affect myocardial contractility or blood pressure significantly.

   – Oxygen Demand Reduction: By lowering heart rate, it decreases the oxygen demand of heart muscles, reducing angina.

  
5. Side Effects
Some individuals may experience side effects while using CORALAN 5 TABLET:

   – Bradycardia: Excessive slowing of the heart rate can cause dizziness or fatigue.

   – Visual Disturbances: Temporary blurred vision or brightness may occur.

   – Gastrointestinal Complaints: Nausea, constipation, or abdominal discomfort are possible.

   – Allergic Reactions: Rare but may include rash or itching.

  
6. Precautions
Certain precautions should be considered before using this medication:

   – Heart Rate Monitoring: Patients with very low resting heart rates should use caution.

   – Liver Function: Dose adjustments may be needed in hepatic impairment.

   – Drug Interactions: May interact with other heart rate-lowering medications; consult your healthcare provider.

   – Pregnancy and Breastfeeding: Use only if clearly needed and under medical supervision.

  
7. Conclusion
In conclusion, CORALAN 5 TABLET is an effective medication to manage chronic stable angina and certain heart failure conditions by selectively reducing heart rate. With careful dosing and medical oversight, it improves symptoms and enhances the quality of life for patients with cardiovascular disease.