DOMPAN TABLET

Ingredent :- Domperidone

Used for :-  DOMPAN TABLET – Used to relieve nausea and vomiting.

Packing of 10 tablets strip

1. Indications
    – Treatment of Gastroesophageal Reflux Disease (GERD): Helps reduce symptoms like heartburn and acid regurgitation.

    – Relief from Nausea and Vomiting: Used in conditions where nausea or vomiting is a major symptom, including postoperative and chemotherapy-induced nausea.

    – Functional Dyspepsia: Provides symptomatic relief for indigestion and bloating due to impaired motility.

    – Gastroparesis: Enhances gastric emptying in patients with delayed stomach emptying, improving digestion and nutrient absorption.
 
2. Benefits
The use of DOMPAN TABLET offers several therapeutic advantages:

    – Improved Gastric Motility: Enhances the contractions of the stomach muscles, aiding in faster movement of food into the intestines.

    – Reduced Nausea and Vomiting: Acts centrally and peripherally to block signals that cause nausea and vomiting.

    – Symptom Relief: Alleviates symptoms such as fullness, bloating, and discomfort associated with gastrointestinal motility disorders.

    – Enhanced Digestion: Supports the digestive process by facilitating smoother movement through the digestive tract.
 
3. Dosage and Administration
It is important to adhere to prescribed dosages to achieve the best results with DOMPAN TABLET:

    – Recommended Dosage: Typically prescribed as 10 mg to 20 mg taken orally three to four times daily, 30 minutes before meals and at bedtime, but exact doses may vary depending on the condition and patient’s response.

    – Administration Instructions: Tablets should be swallowed whole with a glass of water and can be taken with or without food.

    – Missed Dose: Take the missed dose as soon as remembered unless it is near the time of the next dose; do not double doses.
 
4. Mechanism of Action
DOMPAN TABLET works primarily by enhancing the motility of the gastrointestinal tract:

    – Prokinetic Effect: Stimulates the movement of the stomach muscles, promoting gastric emptying and intestinal transit.

    – Dopamine Receptor Antagonist: Blocks dopamine receptors in the gastrointestinal tract and central nervous system, which helps reduce nausea and improve motility.

    – Increased Lower Esophageal Sphincter Tone: Helps prevent acid reflux by tightening the sphincter muscle between the esophagus and stomach.
 
5. Side Effects
Though generally well tolerated, DOMPAN TABLET may cause some side effects in certain individuals:

    – Gastrointestinal: Diarrhea, abdominal cramps, or constipation may occur.

    – Central Nervous System: Drowsiness, fatigue, or dizziness might be experienced, especially at higher doses.

    – Extrapyramidal Symptoms: Rarely, involuntary muscle spasms or tremors can occur, particularly in children or elderly patients.

    – Allergic Reactions: Rash, itching, or swelling can happen rarely; immediate medical help is necessary if severe reactions occur.
 
6. Precautions
Before using DOMPAN TABLET, certain precautions should be observed:

    – Existing Conditions: Patients with epilepsy, Parkinson’s disease, or severe gastrointestinal obstruction should inform their doctor.

    – Drug Interactions: May interact with other CNS depressants or medications affecting heart rhythm; all current medications should be discussed with the healthcare provider.

    – Pregnancy and Lactation: Consult a healthcare professional before use during pregnancy or breastfeeding.
 
7. Conclusion
DOMPAN TABLET is an effective option for managing gastrointestinal motility disorders and associated symptoms such as nausea, vomiting, and acid reflux. By enhancing gastric emptying and blocking dopamine receptors, it helps restore normal digestive function and provides symptom relief. Proper dosage adherence and medical supervision are essential to maximize benefits and minimize adverse effects.