LOBET 100 TABLET

Ingredent :- Labetalol 100 mg

Use for :- LOBET 100 TABLET – Used for managing hypertension.

Units of :- Packing of 10 tablets strip

1. Indications
   – Gastroesophageal Reflux Disease (GERD): Used to treat symptoms of acid reflux, including heartburn and regurgitation.

   – Peptic Ulcers: Helps heal gastric and duodenal ulcers by reducing stomach acidity.

   – Zollinger-Ellison Syndrome: Manages excessive gastric acid secretion caused by gastrin-secreting tumors.

   – Erosive Esophagitis: Promotes healing of esophageal mucosal damage due to acid exposure.

  
2. Benefits
LOBET 100 TABLET provides significant therapeutic benefits in acid-related disorders:

   – Powerful Acid Suppression: Blocks the proton pumps in stomach lining cells, reducing acid secretion effectively.

   – Symptom Relief: Rapidly alleviates symptoms such as heartburn, epigastric pain, and acid regurgitation.

   – Ulcer Healing: Supports mucosal healing and prevents ulcer recurrence.

   – Improved Quality of Life: Reduces discomfort, allowing normal eating and daily activities.

  
3. Dosage and Administration
Correct dosing and timing optimize therapeutic effects:

   – Recommended Dosage: Typically, one tablet once daily before meals, as directed by the healthcare professional.

   – Administration: Taken orally with water. Preferably taken 30 to 60 minutes before the first meal of the day for best results.

   – Missed Dose: Take the missed dose as soon as possible unless it is close to the next dose time. Do not double dose.

  
4. Mechanism of Action
LOBET 100 TABLET acts at the cellular level in the stomach to reduce acid secretion:

   – Proton Pump Inhibition: Irreversibly binds to H+/K+ ATPase enzyme system (“proton pump”) of gastric parietal cells.

   – Acid Secretion Block: This inhibits the final step of acid production, dramatically reducing gastric acidity.

   – Sustained Effect: The inhibition lasts longer than the plasma half-life due to irreversible binding.

  
5. Side Effects
Side effects are usually mild but may include:

   – Gastrointestinal Symptoms: Nausea, diarrhea, abdominal pain, or constipation.

   – Headache or Dizziness: Occasional mild neurological symptoms.

   – Vitamin B12 Deficiency: Long-term use may impair absorption of vitamin B12.

   – Increased Infection Risk: Prolonged acid suppression may slightly increase susceptibility to gastrointestinal infections.

  
6. Precautions
Key precautions for LOBET 100 TABLET use include:

   – Medical History: Inform your doctor if you have liver disease, low magnesium levels, or osteoporosis.

   – Drug Interactions: May interact with certain drugs like clopidogrel, warfarin, or digoxin.

   – Pregnancy and Lactation: Use only if clearly needed and under medical supervision.

   – Long-Term Use: Should be regularly reviewed by a healthcare provider to avoid potential complications.

  
7. Conclusion
In conclusion, LOBET 100 TABLET is an effective proton pump inhibitor for managing acid-related gastrointestinal disorders. It provides potent and sustained acid suppression, leading to symptom relief and healing of ulcers and esophageal damage. When used appropriately under medical guidance, it significantly improves patients’ quality of life by controlling acid reflux and related complications.