Ingredent :- Isoxsuprine
Used for :- TIDILAN RETARD TABLET – Used for treatment of Peripheral vascular disease.
Packing of 10 tablets strip
Indications
– Preterm Labor Management: Helps in preventing premature uterine contractions in pregnancy.
– Threatened Miscarriage: Reduces uterine irritability to maintain pregnancy stability.
– Peripheral Vascular Disease: Improves blood flow in conditions like Raynaud’s phenomenon and atherosclerosis.
– Cerebral Vasospasm: Used in select cases to improve blood flow to the brain.
– Pregnancy-Associated Hypertension: Helps lower vascular resistance, supporting better placental perfusion.
Benefits
offers extended action and consistent symptom relief:
– Sustained Release: The retard (extended release) formulation ensures a longer duration of action, reducing dosing frequency.
– Smooth Muscle Relaxant: Relieves uterine and vascular muscle tension to reduce preterm labor risks.
– Enhanced Circulation: Dilates peripheral vessels to promote better blood flow and oxygenation.
– Support in Pregnancy: Offers reliable control of uterine activity during high-risk pregnancies.
– Reduced Fluctuations: Provides stable plasma levels, reducing side effects compared to immediate-release forms.
Dosage and Administration
Proper use of ensures effectiveness and safety:
– Dosage: Typically one tablet (usually 40 mg or 60 mg as prescribed) is taken once or twice daily.
– Administration: Swallowed whole with water, preferably after meals to reduce gastric irritation.
– Duration: Continued as long as recommended by the physician depending on the condition being treated.
– Missed Dose: If a dose is missed, take it as soon as remembered. If it’s close to the next dose, skip the missed one—do not double the dose.
Mechanism of Action
functions through its long-acting vasodilatory and muscle relaxant effects:
– Calcium Channel Blockade: Inhibits calcium influx in smooth muscles, leading to muscle relaxation.
– Vasodilation: Widens peripheral arteries and reduces resistance, enhancing blood flow.
– Uterine Muscle Relaxation: Suppresses spontaneous uterine contractions, prolonging pregnancy duration when needed.
– Retard Formulation: Ensures slow, sustained drug release for prolonged therapeutic effect.
Side Effects
Though well tolerated, some individuals may experience the following:
– Headache: Common due to vasodilation.
– Dizziness or Fatigue: Especially during initial doses.
– Nausea or Gastric Discomfort: Usually mild and transient.
– Palpitations or Increased Heart Rate: May occur as a reflex to vasodilation.
– Allergic Reactions: Rare; includes rash, itching, or swelling.
Precautions
Certain precautions must be taken while using :
– Cardiovascular Conditions: Use with caution in patients with heart disease or arrhythmias.
– Blood Pressure: Regular monitoring is advised, especially in patients prone to hypotension.
– Pregnancy Use: Should only be used under obstetric guidance during pregnancy.
– Kidney or Liver Dysfunction: Dosage may need adjustment in these patients.
– Drug Interactions: Inform your doctor about any other ongoing medications to avoid adverse interactions.
Conclusion
In conclusion, is a reliable and long-acting therapeutic option for patients requiring prolonged control of uterine contractions or vascular spasms. Its sustained-release profile ensures steady drug levels, making it highly effective in managing high-risk pregnancies and vascular conditions. When used under proper medical supervision, it offers significant benefits with minimal risk.







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