ALBUREL OS 20% 100ML

Ingredent :- Human Albumin

Use for :- ALBUREL OS 20% 100ML – Used for treating low blood volume and protein levels.

Units of :- Packing of 100 ml vial

1. Indications
    – Hypovolemia: For patients with acute blood volume deficits due to hemorrhage, surgery, or trauma .
    – Burns & Critical Illness: Addresses fluid loss and reduced colloid osmotic pressure in extensive burns .
    – Low Blood Proteins: Prescribed in hypoalbuminemia or hypoproteinemia 
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    – Major Surgeries: Used intra- or post-operatively to maintain fluid homeostasis.

 
2. Benefits
    – Stable Circulatory Support: Increases intravascular volume and pressure.
    – Safe Fluid Replacement: Colloid therapy is often more sustained than crystalloids.
    – Helps Perfusion: Improves delivery of oxygen and nutrients after trauma or surgery.
    – Minimal Absorption: Acts only within vascular system, with limited metabolic burden.

 
3. Dosage and Administration
    – Standard Adult Dose: Generally 100 mL (20 g albumin), titrated to clinical response 
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    – Pediatric Use: Dosing based on body weight, guided by physician.
    – Administration: IV infusion under medical supervision; patient monitoring mandatory.
    – Missed Doses: Rare in clinical setup—managed by healthcare team.

 
4. Mechanism of Action
    – Plasma Expansion: Draws fluid into circulation through increased oncotic pressure.
    – Sustained Hemodynamics: Ensures stable blood volume more efficiently than isotonic solutions.
    – Protein Replacement: Restores plasma albumin levels to normal range.
    – Limited Cellular Impact: Functions primarily in plasma without additional metabolic consequences.

 
5. Side Effects
    – Allergic Events: Can cause rash, fever, chills, or anaphylactic reactions .
    – Fluid Overload Risks: Watch for pulmonary edema and hypertension in vulnerable patients .
    – Electrolyte Shifts: May induce imbalances; monitoring required.
    – GI Symptoms & Chills: Occasional mild effects like nausea or chills post-infusion .

 
6. Precautions
    – Vulnerable Populations: Caution in renal/cardiac impairment to prevent volume overload.
    – Infusion Reactions: Administer test dose if allergy suspected.
    – Vital Monitoring: Track blood pressure, electrolytes, and acid–base status during administration.
    – Pregnancy & Lactation: Administer only if clearly needed, under medical oversight.

 
7. Conclusion
ALBUREL OS 20% 100ML offers reliable correction of fluid and protein deficits in acute medical and surgical settings. Its high-concentration formulation provides quick volume support with sustained activity. With responsible dosing and close monitoring, it remains a cornerstone in critical fluid management strategies.