JARDIANCE MET 5/500MG TABLET

Ingredent : Empagliflozin (5 mg) + Metformin Hydrochloride (500 mg)

Use for : JARDIANCE MET 5/500MG TABLET – Used for controlling blood sugar levels.

Units : Packing of 10 Tablets Strip

1. Indications
   – Type 2 Diabetes Mellitus: Prescribed to adults with type 2 diabetes to improve blood sugar levels.
   – Inadequate Glycemic Control: Used when diet, exercise, and Metformin monotherapy fail to maintain blood glucose.
   – Cardiovascular Risk Reduction: Shown to lower the risk of heart failure hospitalization in diabetic patients.
   – Weight & Blood Pressure Management: Offers mild benefits in weight loss and systolic blood pressure control.

2. Benefits
   – Dual Mechanism: Empagliflozin enhances glucose excretion via urine, and Metformin reduces hepatic glucose production.
   – Weight Neutral or Reducing: Helps in moderate weight loss—beneficial in obese type 2 diabetics.
   – Low Hypoglycemia Risk: Unless used with insulin or sulfonylureas, hypoglycemia risk remains low.
   – Kidney & Heart Support: Empagliflozin contributes to kidney protection and cardiovascular stability in long-term use.

3. Dosage and Administration
   – Dosage: Usually taken once or twice daily, based on physician’s advice. Initial dose is often one tablet twice daily.
   – Administration: Should be taken with meals to reduce gastrointestinal side effects.
   – Missed Dose: Take it as soon as possible unless close to the next dose. Do not double up.

4. Mechanism of Action
   – Empagliflozin: Inhibits SGLT2 in the kidney, leading to increased urinary glucose excretion.
   – Metformin: Decreases liver glucose production and improves insulin sensitivity in muscles.

5. Side Effects
   – Common Side Effects: Increased urination, genital infections (especially in females), nausea, and stomach upset.
   – Rare Side Effects: Lactic acidosis (a rare but serious side effect), ketoacidosis, and urinary tract infections.
   – Dehydration: Empagliflozin can cause fluid loss; staying well hydrated is essential.

6. Precautions
   – Renal Function Monitoring: Periodic kidney function tests are required before and during treatment.
   – Avoid in Type 1 Diabetes: Not indicated for patients with type 1 diabetes or diabetic ketoacidosis.
   – Elderly Patients: Use with caution due to risk of volume depletion and renal impairment.
   – Alcohol Use: Limit intake as it may enhance the risk of lactic acidosis.

7. Conclusion
In conclusion, JARDIANCE MET 5/500MG TABLET offers a modern, efficient, and safe option for type 2 diabetes management. Its dual action targets multiple pathways of hyperglycemia, while also contributing to cardiovascular and renal protection. When combined with healthy lifestyle changes, it plays a vital role in long-term diabetes control and overall well-being.