Ingredent :- Methotrexate
Used for :- MEXT 7.5MG TABLET – Used for treating severe psoriasis and rheumatoid arthritis.
Packing of 10 tablets strip
1. Indications
– Rheumatoid Arthritis: Used to reduce joint inflammation, pain, and stiffness in patients with moderate to severe rheumatoid arthritis.
– Psoriasis: Indicated for the treatment of severe, recalcitrant, disabling psoriasis that is not adequately responsive to other forms of therapy.
– Certain Cancers: Sometimes used as part of chemotherapy regimens under specialist supervision for cancers such as leukemia or lymphomas.
2. Benefits
The therapeutic benefits of MEXT 7.5MG TABLET include:
– Immune Modulation: Helps suppress the excessive immune response that leads to autoimmune inflammation and tissue damage.
– Symptom Control: Alleviates pain, swelling, redness, and stiffness associated with inflammatory diseases.
– Disease Progression Delay: Prevents or slows the joint damage and progression in autoimmune diseases.
– Improved Quality of Life: Allows patients to carry out daily activities with reduced discomfort and enhanced mobility.
3. Dosage and Administration
Proper dosing and administration are crucial to ensure efficacy and minimize side effects:
– Dosage: Typically taken once a week, not daily. Dosage must be customized based on the patient’s disease, weight, and response.
– Method: Taken orally with or without food. Swallow whole with water; do not crush or chew.
– Monitoring: Regular blood tests may be required to monitor liver function, blood counts, and kidney function during therapy.
4. Mechanism of Action
MEXT 7.5MG TABLET acts at the cellular level to interfere with DNA synthesis and immune system function:
– Immune Suppression: Reduces activity of immune cells that drive inflammation in autoimmune diseases.
– Anti-Inflammatory Effect: Minimizes inflammatory cytokine production, thereby reducing tissue swelling and pain.
– Anti-Proliferative Activity: In cancer, it slows down the growth of abnormal cells by interfering with cell replication processes.
5. Side Effects
While effective, MEXT 7.5MG TABLET may cause certain side effects in some individuals:
– Gastrointestinal: Nausea, vomiting, abdominal discomfort, or loss of appetite.
– Hematological: May lower blood cell counts, leading to increased risk of infections or bleeding.
– Hepatic: Liver enzyme elevations or liver toxicity may occur with long-term use.
– Others: Mouth sores, dizziness, or fatigue. Rarely, lung or kidney complications may arise.
6. Precautions
Before initiating therapy with MEXT 7.5MG TABLET, the following precautions should be observed:
– Avoid Alcohol: Concurrent alcohol use can increase liver toxicity risk.
– Pregnancy/Breastfeeding: Contraindicated during pregnancy and lactation. Effective contraception should be used during and after treatment.
– Infection Risk: Avoid live vaccines and minimize exposure to infectious agents due to immunosuppressive effects.
– Preexisting Conditions: Not advised in patients with liver disease, kidney disease, or active infections unless closely monitored.
7. Conclusion
In conclusion, MEXT 7.5MG TABLET is a potent disease-modifying therapy for managing autoimmune diseases and some cancers. By suppressing immune overactivity and reducing inflammation, it helps alleviate symptoms and prevent long-term damage. Due to its potential side effects, it requires regular monitoring and should be used strictly under medical supervision. Adherence to dosing schedules and precautionary measures is essential for achieving therapeutic success with minimal complications.







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