NEWSULIN 30/70 INJECTION

Ingredent :- Insulin 30% Regular + 70% NPH

Use for :- NEWSULIN 30/70 INJECTION – Used for the treatment of diabetes mellitus.

Units of :- Packing of 10 ml vial

1. Indications
   – Type 2 Diabetes Mellitus: NEWSULIN 30/70 INJECTION is prescribed for patients with Type 2 diabetes who cannot achieve sufficient glycemic control with oral medications alone.

   – Type 1 Diabetes Mellitus: Used in patients with Type 1 diabetes who require both basal and prandial insulin coverage in a single injection.

   – Combination Therapy: May be used alongside oral hypoglycemic agents under medical supervision.

   – Hyperglycemia Management: Helps manage persistent high blood glucose levels and prevent diabetes-related complications.

  
2. Benefits
NEWSULIN 30/70 INJECTION provides multiple advantages that help patients manage their diabetes effectively:

   – Dual Action Control: Combines both rapid and intermediate-acting insulin for immediate and sustained glucose control.

   – Simplified Regimen: Reduces the need for multiple insulin injections by combining basal and prandial insulin in one dose.

   – Predictable Onset and Duration: Offers consistent onset of action within 30 minutes and duration of up to 24 hours, allowing for better daily glucose management.

   – Reduced Blood Sugar Fluctuations: Helps minimize large fluctuations in blood sugar levels, contributing to better long-term health outcomes.

  
3. Dosage and Administration
Correct dosage and proper administration are critical to achieve desired therapeutic outcomes:

   – Recommended Dosage: The dose is individualized based on the patient’s blood sugar levels, dietary habits, physical activity, and overall condition. Dosage adjustments may be needed over time.

   – Administration: NEWSULIN 30/70 INJECTION is administered subcutaneously, usually 30 minutes before a meal. Preferred injection sites include the abdomen, thigh, upper arm, or buttocks.

   – Rotation of Site: To avoid lipodystrophy (fat tissue changes), rotate the injection site with each dose.

   – Missed Dose: If a dose is missed, consult a physician or follow the recommended patient protocol. Do not double the dose to make up for the missed one.

  
4. Mechanism of Action
NEWSULIN 30/70 INJECTION works by supplementing the body’s deficient insulin production with external insulin:

   – Regular Insulin (30%): Begins acting within 30 minutes to control blood sugar after meals (prandial insulin).

   – Isophane Insulin (70%): Provides prolonged basal insulin coverage by slowly releasing into the bloodstream over 12–24 hours.

   – Blood Glucose Regulation: Facilitates glucose uptake by tissues and suppresses hepatic glucose output, thus lowering blood sugar levels.

  
5. Side Effects
While effective and commonly used, NEWSULIN 30/70 INJECTION may cause side effects in some patients:

   – Hypoglycemia: The most common side effect. Symptoms include sweating, dizziness, confusion, rapid heartbeat, and blurred vision.

   – Local Reactions: Mild pain, redness, or swelling at the injection site.

   – Weight Gain: May cause mild to moderate weight gain due to improved glucose utilization.

   – Lipodystrophy: Prolonged use at the same injection site may cause fat loss or accumulation under the skin.

  
6. Precautions
Several precautions must be taken into account when using NEWSULIN 30/70 INJECTION:

   – Blood Sugar Monitoring: Regular monitoring of blood glucose levels is essential to avoid hypoglycemia or hyperglycemia.

   – Dose Adjustment: Dosage may need adjustment during periods of illness, stress, or changes in physical activity or diet.

   – Drug Interactions: Inform the doctor about any other medications being taken as some drugs can affect insulin sensitivity.

   – Alcohol Use: Alcohol consumption can increase the risk of hypoglycemia and should be avoided or consumed cautiously.

   – Pregnancy and Breastfeeding: Safe for use during pregnancy and breastfeeding when prescribed and monitored by a physician.

  
7. Conclusion
In conclusion, NEWSULIN 30/70 INJECTION is a reliable and effective insulin formulation for managing blood glucose levels in diabetic patients. Its dual-action mechanism simplifies insulin therapy by combining basal and prandial control in a single injection. When used as prescribed, along with lifestyle modifications, it helps patients achieve stable blood sugar levels and reduce the risk of long-term diabetes complications. Proper administration, monitoring, and adherence to dosage are essential for achieving optimal therapeutic outcomes.