TELMIPIL AM TABLET

Ingredent :- Telmisartan + Amlodipine

Use for :-

Units of :- Packing of 10 tablets strip

1. Indications
  – Hypertension: For essential hypertension when single‑drug treatment doesn’t achieve targets.
  – High-Risk Patients: May be prescribed for individuals with additional cardiovascular risk factors.
  – Adults Only: Not to be used in children under 18 unless specifically advised.

 
2. Benefits
TELMIPIL AM TABLET offers:
  – Effective Blood Pressure Control: Combines two mechanisms for better and sustained hypertension reduction.
  – Cardiovascular Protection: Reduces risks of heart attack and stroke by lowering blood pressure.
  – Improved Tolerance: Lower doses of each agent may reduce individual side effects.
  – Convenience: Once-daily dosing enhances compliance.

 
3. Dosage and Administration
General guidelines, but always follow your doctor:
  – Standard Dose: 40 mg telmisartan + 5 mg amlodipine once daily, with or without food.
  – Dose Adjustments: Possible increase to 80/10 mg or reduction (25 mg telmisartan/5 mg amlodipine).
  – Precautions: Take at same time each day, avoid skipping doses, complete course for consistent BP control.
  – Missed Dose: If missed, take as soon as remembered unless close to next dose; do not double dose.

 
4. Mechanism of Action
TELMIPIL AM TABLET lowers blood pressure via dual pathways:
  – Telmisartan (ARB): Blocks angiotensin II receptors → vasodilation & reduced aldosterone.
  – Amlodipine (CCB): Inhibits calcium influx into vascular muscle → vessel relaxation.
  – Synergy: Combined use results in greater BP reduction with fewer side effects.

 
5. Side Effects
Common and rarer effects include:
  – Common: Dizziness, headache, flushing, ankle swelling, fatigue, stomach upset .
  – Orthostatic Hypotension: May cause lightheadedness especially when standing.
  – Rare/Serious: Edema, palpitations, unpredictable allergic reactions.
  – Monitor: Check BP, renal function, and electrolytes periodically.

 
6. Precautions
Critical safety measures:
  – Pregnancy/Lactation: Contraindicated due to risk to fetus and infant .
  – Alcohol: Avoid or limit as it may amplify BP-lowering effects.
  – Organ Function: Use caution in hepatic or renal impairment; may need dose adjustment.
  – Interactions: NSAIDs, diuretics, lithium, digoxin, potassium supplements—monitor closely .
  – Elderly: May require dose adjustment due to increased susceptibility to hypotension.

 
7. Conclusion
In summary, TELMIPIL AM TABLET is a highly effective dual-action antihypertensive suitable for adults inadequately controlled on single agents. It combines telmisartan and amlodipine to reduce blood pressure, protect cardiovascular health, and improve patient adherence. Regular monitoring of blood pressure, kidney function, and electrolytes is essential to ensure long-term safety and effectiveness.