Ingredent :- Diloxanide 500 mg
Use for :- AMICLINE TABLET – Used for worm infections.
Units of :- Packing of 10 tablets strip
1. Indications
– Amoebiasis: AMICLINE TABLET is commonly prescribed for intestinal amoebiasis (dysentery) and liver abscess caused by Entamoeba histolytica.
– Giardiasis: Used to treat giardiasis, an intestinal infection caused by Giardia lamblia, which often results in diarrhea and abdominal cramps.
– Mixed Infections: Effective against infections caused by both protozoa and anaerobic bacteria.
– Prophylaxis: In certain cases, it may be used for the prevention of infection in high-risk individuals, as advised by a physician.
2. Benefits
AMICLINE TABLET provides targeted relief from parasitic and bacterial infections with multiple therapeutic benefits:
– Potent Antiprotozoal Action: Eliminates parasites from the gastrointestinal tract and other affected tissues efficiently.
– Broad-Spectrum Activity: Effective against both protozoal and anaerobic bacterial infections.
– Rapid Symptom Relief: Helps alleviate symptoms such as abdominal pain, diarrhea, and fever typically associated with parasitic infections.
– Tissue Penetration: Reaches both intestinal and extraintestinal tissues, such as the liver, making it effective for deeper infections like amoebic liver abscess.
3. Dosage and Administration
Proper dosage and timely administration are crucial to ensure the complete resolution of the infection:
– Recommended Dosage: The usual adult dosage is determined by the severity and type of infection and should be taken exactly as prescribed by the physician. Dosage may differ in pediatric patients.
– Administration: AMICLINE TABLET should be swallowed whole with water. It may be taken with or after food to minimize stomach discomfort.
– Missed Dose: If a dose is missed, take it as soon as possible. If it’s almost time for the next dose, skip the missed dose. Do not double the dose.
4. Mechanism of Action
AMICLINE TABLET acts by disrupting the life processes of protozoa and certain bacteria:
– DNA Interference: Inhibits nucleic acid synthesis in susceptible organisms, preventing their replication and survival.
– Selective Toxicity: Targets parasitic cells more effectively than human cells, reducing damage to the host while killing the pathogen.
– Systemic Reach: Capable of reaching parasites not just in the intestine but also in tissues such as the liver.
5. Side Effects
Although well-tolerated in most cases, AMICLINE TABLET may cause certain side effects:
– Gastrointestinal Upset: Common side effects include nausea, vomiting, stomach cramps, or metallic taste in the mouth.
– Dizziness or Headache: Some users may experience mild neurological symptoms such as dizziness or headache.
– Allergic Reactions: Rarely, hypersensitivity reactions like rash, itching, or swelling may occur. Seek immediate medical attention if serious allergic symptoms appear.
– Long-Term Use Concerns: Prolonged use may occasionally cause neuropathy or other neurological effects. Follow dosage duration strictly.
6. Precautions
Before using AMICLINE TABLET, certain precautions must be observed:
– Medical History: Inform your doctor about any history of liver disease, neurological disorders, or alcohol use.
– Drug Interactions: May interact with alcohol, anticoagulants, or other antiprotozoal drugs. Avoid alcohol during treatment and for at least 48 hours afterward.
– Pregnancy and Lactation: Should be used under medical supervision during pregnancy or while breastfeeding.
– Renal or Hepatic Impairment: Dose adjustment may be necessary in patients with kidney or liver dysfunction.
7. Conclusion
In conclusion, AMICLINE TABLET is a highly effective treatment option for parasitic and certain bacterial infections, particularly of the gastrointestinal tract. Its potent antiprotozoal properties and systemic reach make it a preferred choice for treating both intestinal and extraintestinal infections. With proper medical guidance and adherence to dosage, patients can expect significant relief from symptoms and complete eradication of the infection.
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