AZIFEEL 500 TABLET

Ingredients :- Azithromycin

AZIFEEL 500 TABLET – Used to treat bacterial infections.

Packing of 10 tablets strip

1. Indications
  - Respiratory Infections: Effective in treating upper and lower respiratory tract infections such as pharyngitis, bronchitis, and pneumonia.
  - Skin and Soft Tissue Infections: Prescribed for conditions like cellulitis, impetigo, and infected wounds.
  - ENT Infections: Commonly used for otitis media, sinusitis, and tonsillitis.
  - Genital Infections: Indicated in uncomplicated cases of urethritis and cervicitis caused by Chlamydia trachomatis.

 
2. Benefits
The use of AZIFEEL 500 TABLET offers numerous therapeutic benefits:

  - Broad-Spectrum Activity: Covers a wide range of gram-positive and gram-negative bacteria.
  - Once-Daily Dosing: Convenient dosing improves compliance, especially for outpatient therapy.
  - Rapid Absorption: High tissue penetration allows faster clinical response.
  - Short Course Therapy: Usually requires only 3 to 5 days of treatment for most infections.

 
3. Dosage and Administration
Proper dosage and administration are essential for optimal therapeutic outcomes:

  - Typical Dosage: One 500 mg tablet once daily for 3 to 5 days, as prescribed by the physician.
  - Administration: Should be taken 1 hour before or 2 hours after food to enhance absorption.
  - Missed Dose: Take as soon as remembered. If it’s near the time for the next dose, skip the missed dose. Do not double up.

 
4. Mechanism of Action
AZIFEEL 500 TABLET works through the following mechanism:

  - Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible bacteria.
  - Prevents the formation of essential proteins, thereby halting bacterial growth.
  - Has a long tissue half-life, maintaining therapeutic levels even after discontinuation.

 
5. Side Effects
While generally safe, some individuals may experience side effects:

  - Gastrointestinal: Nausea, vomiting, abdominal pain, and diarrhea are the most common.
  - Liver Function: Transient elevation in liver enzymes may occur.
  - Allergic Reactions: Rarely, patients may develop rash, itching, or in severe cases, anaphylaxis.
  - Cardiovascular: Prolonged QT interval may occur in predisposed individuals.

 
6. Precautions
Precautions should be taken when using AZIFEEL 500 TABLET:

  - Hepatic Impairment: Use cautiously in patients with liver disease; monitor liver function.
  - Cardiac Conditions: Should be avoided in patients with known QT prolongation or on medications that prolong QT interval.
  - Renal Impairment: Use under medical supervision in those with severe renal dysfunction.
  - Pregnancy and Lactation: Use only if clearly needed and prescribed by a healthcare provider.

 
7. Conclusion
In conclusion, AZIFEEL 500 TABLET is a highly effective macrolide antibiotic used for a range of bacterial infections. Its broad-spectrum activity, excellent tissue penetration, and short-course convenience make it a preferred choice in outpatient settings. With appropriate use under medical guidance, it ensures rapid recovery and a favorable safety profile.