DAPAFLIX M TABLET

Ingredients :- Dapagliflozin + Metformin

DAPAFLIX M TABLET – Used to control high blood sugar levels in people with type 2 diabetes.

Packing of 10 tablets strip

1. Indications
   – Type 2 Diabetes Mellitus: Indicated for patients who require dual therapy to achieve glycemic control, particularly when monotherapy is insufficient.

   – Glycemic Control: Helps in managing elevated blood glucose levels by targeting insulin resistance and promoting urinary glucose excretion.

   – Cardiovascular Risk Reduction: May be prescribed in patients with diabetes who also have a high risk of cardiovascular complications, in accordance with clinical guidelines.

2. Benefits
The use of DAPAFLIX M TABLET offers several clinical and lifestyle-related benefits:

   – Blood Sugar Reduction: Helps lower fasting and post-meal blood glucose levels effectively.

   – Dual Mechanism: Combines two antidiabetic mechanisms—one that improves insulin sensitivity and one that increases urinary glucose excretion.

   – Weight Management: May aid in modest weight loss, which is beneficial in overweight individuals with type 2 diabetes.

   – Low Risk of Hypoglycemia: Due to its glucose-dependent mechanism, it poses a lower risk of causing dangerously low blood sugar compared to other classes.

3. Dosage and Administration
Proper use of DAPAFLIX M TABLET is essential for effective results:

   – Recommended Dosage: Usually taken once daily, preferably with food to reduce gastrointestinal side effects. The dosage depends on the patient’s medical history and current blood glucose levels.

   – Administration: The tablet should be swallowed whole with water and should not be crushed or chewed.

   – Missed Dose: If a dose is missed, take it as soon as remembered. If it’s close to the time for the next dose, skip the missed one and resume the regular schedule. Do not double the dose.

4. Mechanism of Action
DAPAFLIX M TABLET functions by combining two complementary actions:

   – First Agent (SGLT2 Inhibition): Works in the kidneys to block reabsorption of glucose, promoting its excretion through urine and lowering blood sugar levels.

   – Second Agent (Insulin Sensitizer): Enhances insulin sensitivity in the liver and peripheral tissues, improving glucose uptake and reducing hepatic glucose production.

   – Combined Effect: Results in sustained glycemic control without significant risk of hypoglycemia.

5. Side Effects
Though generally well-tolerated, DAPAFLIX M TABLET may cause some side effects:

   – Genitourinary Infections: Increased risk of urinary tract infections and genital fungal infections due to glucose in the urine.

   – Gastrointestinal Discomfort: Nausea, bloating, or diarrhea may occur, especially during the initial phase.

   – Dehydration: Mild dehydration or dizziness can result from increased urination. Adequate hydration is advised.

   – Rare Side Effects: In rare cases, it may cause lactic acidosis or ketoacidosis, requiring immediate medical attention.

6. Precautions
Before using DAPAFLIX M TABLET, consider the following precautions:

   – Kidney Function: Not recommended in patients with moderate to severe renal impairment. Regular monitoring of kidney function is essential.

   – Liver Function: Should be used cautiously in patients with hepatic impairment; dose adjustments may be necessary.

   – Concurrent Medications: May interact with diuretics, antihypertensives, and insulin or insulin secretagogues. Discuss all medications with the doctor.

   – Pregnancy and Lactation: Should not be used during pregnancy or breastfeeding unless clearly advised by a physician.

7. Conclusion
In conclusion, DAPAFLIX M TABLET is an effective dual-action therapy for managing type 2 diabetes in adults. Its complementary mechanisms help reduce blood sugar levels, improve insulin sensitivity, and support cardiovascular health with a relatively low risk of hypoglycemia. Adherence to prescribed dosage, proper lifestyle modifications, and regular monitoring of blood glucose levels are key to achieving long-term therapeutic success and preventing complications associated with diabetes.