METHIROZ PG TABLET

Ingredients :- Methyldopa + Hydrochlorothiazide

METHIROZ PG TABLET – Used for managing hypertension.

Packing of 10 tablets strip

1. Indications
   – Diabetic Neuropathy and Other Nerve Pain: Relieves burning, shooting sensations in hands/feet.

   – Post-Herpetic Neuralgia: Helps alleviate nerve pain persisting after shingles.

   – Peripheral Neuropathy: Recommended for nerve damage from compression, injury, or disease.

   – Radiculopathy (Sciatica): May be prescribed to reduce nerve-root pain in the back or neck.

 
2. Benefits
METHIROZ PG TABLET offers multiple therapeutic benefits:

   – Dual Symptom Relief: Pregabalin eases nerve pain while methylcobalamin supports structural repair.

   – Improved Sleep & Quality of Life: Less pain often leads to better sleep and daytime functioning.

   – Reduced Dependency on Opioids: It serves as a safer alternative for chronic pain management.

   – Neuromodulation: Helps calm overexcited nerve cells and rebuild damaged nerve sheaths.

 
3. Dosage and Administration
Adhere closely to the prescribing doctor’s guidance:

   – Typical Adult Dose: Pregabalin 75 mg plus Methylcobalamin 750 µg – one tablet 1–3 times daily. Your doctor may adjust the dose gradually based on response and tolerance.

   – Administration: Take with water, with or after food. Swallow whole—do not crush or chew.

   – Missed Dose: Take as soon as possible, unless it’s almost time for the next dose. Do not double up.

 
4. Mechanism of Action
The two components act synergistically:

   – Pregabalin: Binds to α2δ subunits of voltage-gated calcium channels in the spinal cord and brain, reducing release of calcium-dependent neurotransmitters and calming nerve hyperactivity.

   – Methylcobalamin: Enables nerve regeneration by aiding myelin sheath synthesis and supporting nerve cell repair.

 
5. Side Effects
Generally well-tolerated, but watch for:

   – Dizziness, Sleepiness or Drowsiness: Common; avoid driving or operating machinery until effects are known.

   – Weight Gain & Increased Appetite: Frequently reported—monitor your diet and exercise.

   – Peripheral Edema: Fluid retention, hands/feet swelling.

   – Gastrointestinal Disturbances: Nausea or constipation; drink water and eat fiber.

 
6. Precautions
Please note the following before use:

   – CNS Effects & Alcohol: Can worsen drowsiness—avoid combining with alcohol .

   – Sudden Withdrawal Risks: Stopping abruptly may trigger anxiety, insomnia, sweating. Gradual tapering is advised.

   – Kidney / Liver Impairment: Dose adjustments may be needed—consult your doctor.

   – Pregnancy & Breastfeeding: Limited data—use only if clearly needed under medical advice.

   – Driving Precautions: Use caution until you ascertain its effects.

 
7. Conclusion
METHIROZ PG TABLET combines proven pain‑relief and nerve-repair actions in a single pill. For individuals struggling with chronic neuropathic pain, this dual-action formula can significantly reduce symptoms and support recovery when taken as prescribed. To get full benefit, adhere to recommended dosing, lifestyle guidance, and regular follow-up with your doctor. Immediate medical attention is advised if severe side effects or allergic reactions occur.