VALPACT 300 TABLET

Ingredent :- Sodium Valproate

Use for :- VALPACT 300 TABLET – Used for treating epilepsy.

Units of :- Packing of 10 tablets strip

1. Indications
   – Epilepsy: Treatment of generalized and partial seizures where higher doses are required for effective control.

   – Bipolar Disorder: Management of acute mania and maintenance therapy to prevent relapse.

   – Migraine Prevention: Used to reduce the number and severity of migraine headaches.

   – Additional Neurological Conditions: Sometimes used off-label for neuropathic pain and other disorders.

  
2. Benefits
The 300 mg dosage strength provides enhanced therapeutic benefits:

   – Improved Seizure Control: Suitable for patients requiring stronger dose for seizure suppression.

   – Enhanced Mood Stabilization: Helps maintain stable mood and reduce the frequency of manic episodes.

   – Effective Migraine Management: Provides better prophylaxis for frequent or severe migraines.

   – Convenience: Higher dose tablets reduce the number of tablets needed daily, improving compliance.

  
3. Dosage and Administration
Dosage must be individualized based on clinical response and tolerance:

   – Recommended Dosage: Typically prescribed for adults requiring higher maintenance doses. Dosage adjustments are made gradually by the physician.

   – Administration: Taken orally with water, preferably with food to minimize gastrointestinal upset.

   – Missed Dose: Take as soon as possible unless it is near the time of the next dose; do not double dose.

  
4. Mechanism of Action
VALPACT 300 TABLET works by similar mechanisms as the lower dose:

   – Enhances GABAergic Activity: Increases inhibitory neurotransmitter activity to calm neuronal excitability.

   – Stabilizes Neuronal Membranes: Modulates voltage-gated sodium channels, preventing abnormal nerve firing.

   – Mood Regulation: Influences neurotransmitter balance to stabilize mood fluctuations.

  
5. Side Effects
Side effects may be dose-dependent and include:

   – Gastrointestinal Symptoms: Nausea, vomiting, and abdominal pain.

   – CNS Effects: Drowsiness, dizziness, tremor, or coordination problems.

   – Serious Reactions: Rare but serious effects such as liver damage, pancreatitis, and allergic reactions require immediate medical attention.

  
6. Precautions
Important precautions include:

   – Liver Monitoring: Liver function tests should be conducted regularly.

   – Pregnancy and Breastfeeding: Use only if benefits outweigh risks, under medical supervision.

   – Drug Interactions: Caution with concomitant medications, including other anticonvulsants and blood thinners.

   – Avoid Alcohol: To reduce CNS side effects.

  
7. Conclusion
In conclusion, VALPACT 300 TABLET provides effective management of seizures, mood disorders, and migraines at a higher dose level. It allows patients requiring stronger therapeutic effect to achieve better symptom control. Adherence to medical advice and regular monitoring ensures safe and effective treatment with this medication.